Proteoglycans-PG e. Its shape in 3D is similar to the bottle washing brush and its molecular weight million Da is mostly due to the sugar side chains.
N-linked oligosacharids. The protein has three globular domains, and between the second and third domain expands the long chondroitin glucosamine sports protein line covered by negatively charged sugar side chains.
PG is attached to a long sugar molecule hyaluronic acidsecured by the link protein.
Up to PG molecules may be attached to a hyaluronic molecule aggregated — aggrecan. Cartilage supporting dietary supplements are widely known. The two major type is chondroitin sulfate and glucosamine.
Chondroitin sulfate is a sulfated GAG of a polymer composed of two alternating sugar molecules N-acetilgalactosamine and glucuronic acid. The sugar polymer may contain up to a hundred sugar molecules, hence only a small fraction of the oral intake will be absorbed. Many recent large scale studies question the real therapeutical effect of chondroitin sulfate.
Glucosamine sulfate is a well known dietary supplement in osteoarthritis. Many well conducted studies show its effectiveness in the treatment of osteoarthritis. Add to bookmark © www.
A projekt az EU társfinanszírozásával, az Európa Terv keretében valósul meg. Ez az oldal a GVOP - 3.
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